
Seeing the Unseen
Publications
18. Water structure and electric fields at the interface of oil droplets
L. Shi+,*, R. A. LaCour+, N. Qian, J. P. Heindel, X. Lang, R. Zhao,
T. Head-Gordon*, W. Min*, Nature, 2025
* co-corresponding author
17. Merging vibrational spectroscopy with fluorescence microscopy: combining the best of two worlds
N. Qian*, H. Xiong*, L. Wei*, L. Shi*, W. Min*, Annu. Rev. Phys. Chem., 2025, 76
* co-corresponding author
16. Viewing 3D spatial biology with highly-multiplexed Raman imaging: from spectroscopy to biotechnology
Y. Li, Y. Sun, L. Shi*, Chem Comm, 2024, 60, 8658-8669, invited review
Breaking Boundaries in 3D Biology: The Power of Highly-Multiplexed Raman Imaging
15. Probing the structure of water in individual living cells
X. Lang, L. Shi, Z. Zhao, W. Min*, Nat. Commun., 2024, 15, 5271-5282
14. VIBRANT: spectral profiling for single-cell drug responses
X. Liu, L. Shi, Z. Zhao, W. Min*, Nat. Methods, 2024, 21, 501-511
13. Vibrational solvatochromism study of the C-H…O improper hydrogen bond
L. Shi*, W. Min*, J. Phys. Chem. B, 2023, 127, 17, 3798-3805
* co-corresponding author
Prior to Fudan:
12. Highly-multiplexed volumetric mapping with Raman dye imaging and tissue clearing
L. Shi+, M. Wei+, Y. Miao, N. Qian, L. Shi, R. Singer, R. Benninger, W. Min*, Nat. Biotechnol., 2022, 40, 264-373
11. Super-resolution vibrational imaging using expansion stimulated Raman scattering microscopy
L. Shi, A. Klimas, B. Gallagher, Z. Cheng, F. Fu, P. Wijesekara, Y. Miao, X. Ren, Y. Zhao*, W. Min*, Adv. Sci., 2022, 2200315
10. Towards mapping mouse metabolic tissue atlas by mid-infrared imaging with heavy water labeling
X. Liu, L. Shi, L. Shi, M. Wei, Z. Zhao, W. Min*, Adv. Sci., 2022, 2105437
9. Highly-multiplexed tissue imaging with Raman dyes
L. Shi, M. Wei, W. Min*, J. Vis. Exp. 2022, (182), e63547, doi:10.3791/63547
8. 9-Cyanopyronin probe palette for super-multiplexed vibrational imaging
Y. Miao, N. Qian, L. Shi, F. Hu, W. Min*, Nat. Commun., 2021, 12, 4518
7. Mid-infrared metabolic imaging with vibrational probes
L. Shi, X. Liu, L. Shi, H. T. Stinson, J. Rowlette, L. J. Kahl, C. R. Evans, C. Zheng, L. E. P. Dietrich, W. Min*, Nat. Methods, 2020, 17, 844-851
6. Optically mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy
L. Shi, F. Hu, W. Min*, Nat. Commun., 2019, 10 (1), 1-8
5. Biological imaging of chemical bonds by stimulated Raman scattering microscopy
F. Hu+, L. Shi+, W. Min*, Nat. Methods, 2019, 16, 830-842. Invited perspective
4. Stimulated Raman excited fluorescence spectroscopy and imaging
H. Xiong+, L. Shi+, L. Wei, Y. Shen, R. Long, Z. Zhao, W. Min*, Nat. Photonics., 2019, 13, 412-417
“Spectroscopy method combines the best of Raman and fluorescence” featured by Chem&Engn News.
3. Probe design for super-multiplexed vibrational imaging
Y. Miao, L. Shi, F. Hu, W. Min*, Phys. Biol. 2019, 16 (4), 041003
2. Electronic resonant stimulated Raman scattering micro-spectroscopy
L. Shi, H. Xiong, Y. Shen, R. Long, L. Wei, W. Min*, J. Phys. Chem. B, 2018, 122 (39), 9218-9224
1. Super-multiplex vibrational imaging
L. Wei, Z. Chen, L. Shi, R. Long, A. V. Anzalone, L. Zhang, F. Hu, R. Yuste, V. W. Cornish and W. Min*, Nature, 2017, 544, 465-470